Full New Update GH Monday, 9/22/2025 Episode (Sept 22, 2025) General Hospital Spoilers
The quiet halls of General Hospital rarely stay still for long, and this Monday’s episode proves just how quickly the calm can collapse into chaos. On September 22, General Hospital delivers an hour that will shake Port Charles to its very core, leaving families fractured, alliances under strain, and long-buried secrets clawing their way to the surface.
What begins as whispers in the corridors soon explodes into revelations no one is prepared to face.
Monica Cordain’s Death: A Loss That Feels Like Betrayal
The episode opens with Elizabeth Webber emerging into the hospital corridor, her hands trembling, her face pale. The words she carries are almost too heavy to speak aloud: Monica Cordain, the formidable matriarch of one of Port Charles’ most complicated families, has passed away.
But grief does not arrive gently here. Instead, it comes tainted with suspicion. Elizabeth breaks the news to Drew Cain, Monica’s adopted son, and the moment should be one of sorrow. Yet Drew listens in chilling silence, his jaw tight, his expression unreadable.
The truth is that Drew and Monica’s bond fractured long before this moment. She had cut him out of her life, stripped him of his place in the family, and left scars that ran deeper than blood. For Drew, grief flickers briefly — but then something darker takes root.
Drew does not see Monica’s death as an accident or the natural closing of a life. He suspects orchestration, perhaps even assassination cloaked as illness. And if anyone dared press him, he might even whisper that the order could have come from him. It’s a thought too horrifying to say aloud, yet Drew wears it like armor. Why mourn a woman who had banished him, when her absence could mean power reclaimed?
Drew and Danny: A Bargain in Blood
The ripple effects begin almost instantly. Danny Morgan approaches Drew, not as a nephew, but as a desperate father. He pleads for Scout Cain, Monica’s granddaughter, to attend the funeral. For Danny, Scout deserves to say goodbye — to honor Monica as part of the family, whatever the fractures.
But Drew’s response is ice. He refuses. To him, the Cordains are a curse — a cycle of betrayal, ruin, and manipulation. He swears Scout will not be dragged back into the chaos that consumed so many before her.
Danny pushes harder, desperation rising, until finally he offers something Drew cannot ignore: a secret. One powerful enough to shift everything. The catch? Drew must allow Scout to attend the funeral in exchange. Drew’s silence as he weighs this gamble is more dangerous than any threat, his eyes revealing calculation rather than compassion.
Lulu Spencer’s Haunting Vision: Nathan West Returns?
Across town, another shockwave strikes. Lulu Spencer dials 911 with trembling hands, her voice frantic as she reports a horrific car accident. When Detective Harrison Chase arrives, Lulu is pale and breathless, her words stumbling out too fast to contain. She swears she saw the victim’s face — and it was Nathan West.
The problem? Nathan has been dead for years.
Chase steadies her, but inside his blood runs cold. If Lulu is right, then reality itself is bending. Was it truly Nathan in that wreckage, alive against all odds? Or is Port Charles once again haunted by ghosts that refuse to stay buried? Lulu insists on what she saw, her conviction rattling Chase and sparking dangerous new questions. If Nathan’s return is real, is it a miracle — or a curse?
Jason Morgan: Grief and a Bloodstained Letter
Meanwhile, Jason Morgan receives word of Monica’s death, and unlike Drew, his grief is raw, quiet, and real. Regret coils inside him, heavy and suffocating. He hadn’t spent enough time with her, hadn’t chosen family over the endless missions and battles that defined his life. Now it is too late.
Yet as Jason moves through the hospital, his grief is pierced by discovery. In Monica’s belongings he stumbles upon a sealed letter, the edges stained crimson like dried blood. Inside lies a revelation that shakes him to his core: Jason and Drew’s biological mother may still be alive — and could already be making her way back to Port Charles.
This bombshell has the potential to rip the Cordain family tree wide open, forcing Jason to confront a past he thought was buried forever. And if Monica’s words are true, then the arrival of this woman could ignite new wars within an already broken dynasty.
Tracy Cordain: Duty in the Face of Loss
Back at the mansion, Tracy Cordain does what she always does in times of crisis — she takes control. Funeral arrangements fall to her, and she moves with brisk efficiency, hiding her grief behind lists, logistics, and sharp commands. But beneath her iron grip is a woman wounded by the loss of her sister.
Tracy may seem unshakable, but her every step feels like preparation not only for Monica’s farewell, but for the unraveling of the family itself.
Michael and Willow: A Family Fractured
Elsewhere, Michael Corinthos struggles with his own storm. He offers Jason condolences, but when he returns home, his grief twists into fury. Confronting Willow Tate, Michael declares with venom that she will never gain custody of their children. His voice rises, his rage uncontrollable, and his words cut like knives.
This outburst is about more than Willow — it is about Michael’s fear of losing everything he loves. He has faced prison, been accused of crimes, and considered worst-case scenarios. In his darkest thoughts, he has even chosen Carly Spencer as guardian of his children if he were ever taken away.
For Willow, Michael’s fury is devastating. The man she thought she knew — the partner she believed would fight with love rather than rage — is slipping away. Their fracture deepens, and Monica’s death only magnifies the chaos.
Anna vs. Laura: One Villain or Many?
While grief grips some, others turn to investigation. Anna Devane follows her instincts, piecing together connections others refuse to see. To her, the attack on Judge Eva Herren and the shooting of Drew are not separate crimes. They bear the signature of a single hand.
But Laura Collins pushes back. The evidence, she argues, points to differences too significant to ignore. Could there be two attackers? Or perhaps a larger network manipulating the trail?
The debate sends ripples of paranoia through Port Charles. Whispers of Sonny Corinthos and Brick surface — not as direct killers, but as men who may unknowingly be part of a far darker game.
Smaller Storms: Love, Loss, and Outback
Even amidst chaos, life in Port Charles refuses to slow. Molly Lansing-Davis finalizes her decision to return Outback the dog to Gio Palmieri and Emma. Cody Bell protests, his heart unwilling to part with the creature, but Molly insists.
The reunion between Gio and Emma is bittersweet relief that soon deepens into intimacy. Their night together is charged with renewed connection, sealing wounds with whispered promises.
A Funeral That Will Change Everything
As the day of Monica’s funeral looms, Port Charles trembles. The sky hangs gray, heavy with unease. Scout arrives under Danny’s watchful eye, her presence stirring emotions Drew refuses to name. Jason keeps Monica’s bloodstained letter secret, knowing its revelation could shatter everything. Lulu remains haunted by Nathan’s face, refusing to let the vision die.
Every character carries secrets, grief, or fury — and all roads lead to the funeral, which promises not closure, but collision.
Monica Cordain may be gone, but her shadow stretches across every corner of Port Charles. Her absence is not silence. It is the spark that threatens to set the entire city ablaze.